منابع مشابه
Candida albicans pathogenicity mechanisms
The polymorphic fungus Candida albicans is a member of the normal human microbiome. In most individuals, C. albicans resides as a lifelong, harmless commensal. Under certain circumstances, however, C. albicans can cause infections that range from superficial infections of the skin to life-threatening systemic infections. Several factors and activities have been identified which contribute to th...
متن کاملClinical and pathogenicity aspects of Candida species
Candida species normally exist as commensals of the skin and mucosa, but they are also opportunistic pathogens, with the ability to cause a variety of superficial and invasive diseases. Among the several of Candida species, Candida albicans remains the most common fungal isolate, mainly from blood cultures in the diagnostic of nosocomial bloodstream infection. However, the rates of candida infe...
متن کاملCandida albicans Pathogenicity and Epithelial Immunity
Candida species are one of the most common fungal pathogens of humans and the causative agents of superficial and invasive candidiasis. The vast majority of Candida infections are mucosal, manifesting as vaginal or oral candidiasis, which together account for an estimated 40 million infections per year. High-level Candida colonisation is also associated with several gut diseases, including Croh...
متن کاملCandida albicans: genetics, dimorphism and pathogenicity.
Candida albicans is a dimorphic fungus that causes severe opportunistic infections in humans. Recent advances in molecular biology techniques applied to this organism (transformation systems, gene disruption strategies, new reporter systems, regulatable promoters) allow a better knowledge of both the molecular basis of dimorphism and the role of specific genes in Candida morphogenesis. These sa...
متن کاملCandida adherence phenomena, from commensalism to pathogenicity.
Molecules present in the most external layers of Candida cells are essential for the adherence to host surfaces, playing a pivotal role in the pathophysiology of candidiasis. Receptors for fibrinogen, fibronectin and other components of the extracellular matrix have been described in Candida surfaces. Their expression may be influenced by particular host conditions, and these changes may be imp...
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ژورنال
عنوان ژورنال: Journal of Bacteriology
سال: 1961
ISSN: 0021-9193,1098-5530
DOI: 10.1128/jb.81.4.550-556.1961